Table 2

Distribution and logistic regression analysis of the p16 exon 3 genotypes and allele frequencies in SCCHN patients and controls

GenotypeCases (n = 208)Controls (n = 224)Crude OR (95% CI)Adjusteda OR (95% CI)
Number%Number%
C540G
 CC16076.917276.81.001.00
 CG4622.14921.91.01 (0.64–1.59)1.01 (0.64–1.61)
 GG21.031.30.72 (0.12–4.35)0.74 (0.12–4.57)
 CG/GG4823.15223.20.99 (0.63–1.55)1.00 (0.64–1.57)
G allele frequencyb0.1200.123
C580T
 CC17483.618582.61.001.00
 CT3315.93716.50.95 (0.57–1.58)0.97 (0.58–1.64)
 TT10.520.90.53 (0.05–5.92)0.49 (0.04–5.49)
 CT/TT3416.43917.40.93 (0.56–1.54)0.94 (0.57–1.58)
T allele frequencyb0.0840.092
  • a Adjusted for age, sex, smoking status, and alcohol use.

  • b Two-sided χ2 test: for 540G allele frequency, P = 0.976; for C540G genotype distribution, P = 0.934; for 580T allele frequency, P = 0.768; and for C580T genotype distribution, P = 0.858.