Table 3

Multivariate-adjusteda risk estimates for patterns of cigarette smoking and alcohol intake among female and male subjects in the pooled analysis

Advanced adenoma cases relative to polyp-free controls OR (95% CI)Nonadvanced adenoma cases relative to polyp-free controls OR (95% CI)Advanced adenoma cases relative to nonadvanced adenoma cases OR (95% CI)
Smoking habits
 Years of smoking
  <151.1 (0.6–2.1)1.2 (0.9–1.8)0.9 (0.5–1.7)
  15–<251.0 (0.5–2.0)1.0 (0.7–1.5)1.0 (0.5–2.0)
  25–<350.9 (0.5–1.9)1.0 (0.7–1.5)0.9 (0.4–1.9)
  ≥351.2 (0.7–2.2)1.4 (1.0–2.0)0.9 (0.5–1.6)
 Number of cigs/day
  <101.2 (0.7–2.2)0.9 (0.7–1.4)1.3 (0.7–2.4)
  10–<200.7 (0.4–1.4)1.3 (1.0–1.8)0.6 (0.3–1.1)
  21–<300.9 (0.4–2.3)1.3 (0.8–2.2)0.7 (0.3–1.8)
  ≥301.4 (0.7–2.6)1.2 (0.8–1.8)1.1 (0.6–2.2)
 Smoking > 20 yrs ago
  <16 pack yrs1.0 (0.6–1.9)1.1 (0.8–1.5)1.0 (0.5–1.8)
  ≥16 pack yrs0.6 (0.3–1.2)1.0 (0.7–1.6)0.5 (0.2–1.8)
 Smoking ≤20 yrs ago
  <10 pack yrs1.1 (0.5–2.2)0.9 (0.6–1.4)1.1 (0.5–2.5)
  10–< 20 pack yrs2.1 (1.0–4.5)1.2 (0.8–1.9)1.7 (0.8–3.9)
  ≥20 pack yrs1.4 (0.6–3.4)1.2 (0.7–1.8)1.3 (0.5–3.1)
Drinking habits
 Beer
  Nondrinker1.01.0
  <4 bottles/cans/week1.3 (0.7–2.6)1.2 (0.8–1.8)1.1 (0.6–2.3)
  ≥4 bottles/cans/week1.7 (0.9–3.2)1.1 (0.7–1.6)1.6 (0.8–3.1)
 Wine
  Nondrinker1.01.0
  <2 glasses per week1.1 (0.5–2.5)1.1 (0.7–1.8)1.0 (0.4–2.3)
  ≥2 glasses per week0.8 (0.4–1.3)1.0 (0.7–1.4)0.8 (0.4–1.4)
 Liquor
  Nondrinker1.01.0
  <3 shots per week1.8 (0.9–3.4)1.1 (0.7–1.6)1.6 (0.8–3.3)
  ≥3 shots per week1.2 (0.7–2.0)1.0 (0.8–1.4)1.2 (0.7–2.0)
  • a All estimates reflect adjustment for age, study site, gender, race, body mass index, total energy intake, total fiber intake, leisure activity, and HRT use.