Table 2

Multivariate-adjusteda ORs for the pooled analysis of risk factors for advanced and nonadvanced adenomas among female and male subjects combined

Advanced adenoma cases relative to polyp-free controls OR (95% CI)Nonadvanced adenoma cases relative to polyp- free controls OR (95% CI)Advanced cases relative to nonadvanced adenoma cases OR (95% CI)
Smoking status
 Never1.01.0
 Former1.0 (0.6–1.5)1.1 (0.9–1.5)0.9 (0.5–2.0)
 Current1.4 (0.8–2.6)1.4 (0.9–2.0)1.0 (0.5–2.0)
Body mass index
 First quartile (lowest)1.01.0
 Second quartile1.3 (0.7–2.3)2.0 (1.4–2.8)0.7 (0.4–1.4)
 Third quartile1.4 (0.8–2.6)1.7 (1.2–2.5)0.8 (0.4–1.2)
 Fourth quartile (highest)2.1 (1.1–3.9)2.0 (1.4–2.9)1.1 (0.6–1.5)
Dietary fiber
 First quartile (lowest)1.01.0
 Second quartile0.9 (0.5–1.6)0.9 (0.7–1.3)0.9 (0.5–1.7)
 Third quartile1.0 (0.6–1.9)1.0 (0.7–1.5)1.0 (0.5–1.9)
 Fourth quartile (highest)1.0 (0.5–2.2)0.6 (0.4–1.0)1.6 (0.7–3.6)
Leisure Activity
 Among women
  Less than 2 h/week1.01.0
  More than 2 h/week1.6 (0.7–3.6)1.1 (0.6–1.7)1.5 (0.6–3.9)
 Among men
  Less than 2 h/week1.01.0
  More than 2 h/week0.4 (0.2–1.0)0.8 (0.5–1.2)0.5 (0.2–1.3)
Use of HRT among women
 Never1.01.0
 Ever0.4 (0.2–0.9)0.7 (0.4–1.0)0.6 (0.2–1.4)
  • a All estimates reflect adjustment for age, study site, gender, race, total energy intake, and all other variables in table.