Table 5

Dietary associationsa between cases with p53 mutations by location and functional definitions compared with controls

OR (referent)OR (95% CI)OR (95% CI)P trend
GI/SugarLowIntermediateHigh
Location
 Arg2731.001.16 (0.58–2.32)1.77 (0.84–3.73)0.03
 Arg2481.001.51 (0.74–3.10)1.35 (0.60–3.07)0.94
 L2 loop1.001.13 (0.61–2.09)2.11 (1.11–4.01)<0.01
 L3 loop1.001.49 (0.87–2.57)1.51 (0.82–2.78)0.88
 LSH1.001.13 (0.43–3.01)1.48 (0.48–4.21)0.10
Function
 DNA contact1.001.31 (0.80–2.14)1.53 (0.89–2.65)0.16
 Protein structure1.001.36 (0.97–1.90)1.78 (1.23–2.57)<0.01
 Denature1.001.44 (0.82–2.52)1.46 (0.78–2.74)0.37
Red meat/fast food/ trans-fatty acid
Location
 Arg2731.001.29 (0.69–2.42)1.83 (0.90–3.70)0.02
 Arg2481.000.75 (0.43–1.31)1.26 (0.67–2.39)0.68
 L2 loop1.002.20 (1.15–4.22)3.42 (1.70–6.86)<0.01
 L3 loop1.000.93 (0.60–1.45)1.54 (0.94–2.54)0.26
 LSH1.002.19 (0.75–6.41)2.93 (0.91–9.49)0.06
Function
 DNA contact1.000.95 (0.63–1.42)1.44 (0.90–2.30)0.08
 Protein structure1.001.47 (1.08–2.01)2.19 (1.55–3.08)<0.01
 Denature1.001.06 (0.66–1.69)1.65 (0.97–2.80)0.11
  • a Adjusted for age and gender.