Table 3

Effects of 3 months of treatment with letrozole on mean serum lipids and bone resorption marker-CTx levels in 27 volunteers

Geometric means were used for CTx and HDL, and arithmetic means were used for LDL and cholesterol. Ps are as described in Table 1<$REFLINK> .

AnalyteTimeMean (95% CI)P (w)
Cholesterol (mmol/liter)Pretreatment5.6 (5.3–5.9)
12 wks5.7 (5.3–6.0)0.6
LDL (mmol/liter)Pretreatment3.8 (3.5–4.1)
12 wks3.8 (3.5–4.1)0.6
HDL (mmol/liter)Pretreatment1.3 (1.2–1.4)
12 wks1.4 (1.2–1.5)0.08
CTx (pmol/liter)Pretreatment1900.7 (1500.3–2388.4)
12 wks2368.5 (1986.5–2833.5) 0.02
  • a Bold indicates significant P.