Table 2

Description of population by p53 mutation status

p53 mutation (n = 686) n (%)p53 Wt (n = 772) n (%)Controls (n = 2410) n (%)
Age
 <5058 (8.5)61 (7.9)229 (9.5)
 51–64244 (35.6)260 (33.7)760 (31.5)
 65–69132 (19.2)142 (18.4)489 (20.3)
 70–79252 (36.7)309 (40.0)932 (38.7)
 χ2a0.240.28
Gender
 Men384 (56.9)409 (53.0)1290 (53.5)
 Women302 (44.0)363 (47.0)1120 (46.5)
 χ20.270.79
Aspirin/NSAID (regular use)
 No420 (61.2)481 (62.3)1260 (52.3)
 Yes266 (38.8)291 (37.7)1150 (47.7)
 χ2<0.01<0.01
Cigarette smoking status
 Never281 (41.2)337 (43.8)1121 (46.6)
 <20 cigarettes/day135 (19.8)142 (18.5)498 (20.7)
 ≥20 cigarettes/day266 (39.0)290 (37.7)786 (32.7)
 χ2<0.010.03
BMI [wt (kg)/ht (m)2]
 <25235 (34.3)252 (32.6)955 (39.6)
 25–29217 (31.7)281 (36.4)831 (34.5)
 >29234 (34.2)239 (31.0)624 (25.9)
 χ2<0.01<0.01
Long-term vigorous physical activity
 None189 (27.6)214 (27.7)535 (22.2)
 Intermediate277 (40.4)329 (42.6)985 (40.9)
 High220 (32.1)229 (29.7)890 (36.9)
 χ2<0.01<0.01
  • a χ2 compares p53 mutation to control and p53 Wt to control.