Table 3

Least square geometric mean hormone levelsa among postmenopausal controls by CYP1B1 genotypes

HormonesGenotypesOverallb (n)
Estrone sulfate (pg/ml)ml: val/val193.33 (28)
val/leu + leu/leu189.97 (119)
P = 0.89
m2: asn/asn187.31 (95)
asn/ser + ser/ser200.09 (43)
P = 0.54
Estrone (pg/ml)ml: val/val29.57 (28)
val/leu + leu/leu29.47 (119)
P = 0.96
m2: asn/asn28.60 (98)
asn/ser + ser/ser31.63 (49)
P = 0.10
Estradiol (pg/ml)ml: val/val6.44 (28)
val/leu + leu/leu7.62 (119)
P = 0.05
m2: asn/asn7.06 (97)
asn/ser + ser/ser8.22 (49)
P = 0.03
  • a Subjects with missing hormone levels removed from analysis; hence, numbers vary slightly by hormone.

  • b Controlling for age, date of blood draw, time of blood draw, fasting status, BMI, and laboratory batch.