Table 2

Adjusted ORs and 95% CIs for prostate cancer by CYP17 genotype stratified by race

GenotypeNo. cases (%)No. controls (%)OR (95% CI)
All subjects
 A1/A1238 (40.3)194 (36.1)1.00a
 A1/A2266 (45.1)263 (48.9)0.81 (0.63–1.05)
 A2/A286 (14.6)81 (15.1)0.87 (0.61–1.26)
Caucasians
 A1/A1228 (40.7)188 (35.9)1.00b
 A1/A2248 (44.3)256 (48.9)0.80 (0.61–1.04)
 A2/A284 (15.0)79 (15.1)0.88 (0.61–1.27)
African-Americans
 A1/A110 (33.3)6 (40.0)1.00b
 A1/A218 (60.0)7 (46.7)1.41 (0.35–5.68)
 A2/A22 (6.7)2 (13.3)0.63 (0.06–6.56)
  • a Adjusted for age, race, and first-degree family history of prostate cancer.

  • b Adjusted for age and first-degree family history of prostate cancer.