Table 3

Logistic regression analysis of XRCC1 codon 399 polymorphism in lung cancer

GenotypeAll casesSquamous cell carcinoma cases
Crude OR (CI)Adjusteda OR (CI)Crude OR (CI)Adjusted OR (CI)
Arg/Arg1.001.001.001.00
Arg/Gln1.27 (0.81–2.04)1.28 (0.80–2.05)1.52 (0.89–2.60)1.45 (0.84–2.50)
Gln/Gln2.30 (0.87–6.09)2.02 (0.75–5.43)3.71 (1.34–10.26)b3.26 (1.17–9.15)
Arg/Gln + Gln/Gln1.40 (0.89–2.18)1.36 (0.87–2.15)1.77 (1.06–2.93)1.66 (0.99–2.79)
  • a Adjusted for age and pack-years of smoking.

  • b Linear association by Mantel-Haenszel χ2 test, χ2 = 7.3; P = 0.007.