Table 2

Comparison of pre- and posttreatment parameters in treated patients

ParameterBaseline (pretreatment) n = 20Posttreatment n = 19a
Mean ± SD
PSA (μg/liter)10.9 ± 9.911.3 ± 10.5
Gleason score6.6 ± 0.86.7 ± 1.0b
Testosterone (nmol/liter)12.1 ± 3.512.1 ± 3.2b
Median (range)
n = 20n = 19a
Excreted Isoflavones
Biochanin A (mg)0.0 (0.0, 0.0)2.1 (0.2, 5.5)c
Daidzein (mg)0.3 (0.0, 5.7)10.9 (1.4, 39.7)c
Formononetin (mg)0 (0.0, 0.2)2.1 (0.1, 7.9)c
Genistein (mg)0.4 (0.0, 4.5)3.6 (0.2, 13.7)c
Total isoflavones (mg)0.7 (0.0, 10.2)19.6 (1.9, 59.4)c
Coagulation factors
INRd1.0 (1.0, 1.2)1.0 (1.0, 1.1)b
APTT (s)e30.5 (27.0, 36.0)30.0 (24.0, 36.0)b
Fibrinogen (g/liter)2.7 (2.0, 4.3)2.4 (1.9, 4.1)b
Hematology
Hemoglobin (g/liter)148.5 (119.0, 157.0)132.0 (107.0, 149.0)c
White cell count (× 109/liter)6.3 (4.7, 9.2)6.5 (4.8, 11.5)
Platelets (×109/liter)217.5 (144.0, 430.0)224.0 (169.0, 417.0)
Biochemistry
Sodium (mmol/liter)139.5 (137.0, 148.0)141.0 (137.0, 145.0)
Potassium (mmol/liter)4.1 (3.8, 4.9)4.1 (3.6, 5.4)
Creatinine (μmol/liter)90.0 (63.0, 122.0)85.5 (65.0, 107.0)b
Urea (mmol/liter)6.7 (3.7, 10.4)6.2 (2.8, 7.6)b
  • a n = 19 excluding patient ID4.

  • b n = 18 excluding both patients ID4 and ID10.

  • c P < 0.0001: nonparametric sign test to test changes from pretreatment to posttreatment.

  • d INR: International Normalized Ratio.

  • e aPTT: Activated partial thromboplastin time.