Table 4

Joint association of aspirin and NSAID use and breast cancer incidencea

Aspirinb
Nonusers<1–5 per week6+ per week
Nonusers10.790.74
(Referent)(0.65–0.97)0.57–0.95)
NSAID
 <1–5 per week0.690.920.57
(0.48–0.98)(0.73–1.15)(0.39–0.85)
 6+ per week1.110.760.6
(0.83–1.50)(0.54–1.08)(0.38–0.97)
  • a Adjusted for age (continuous), BMI (continuous), estrogen use (current or not current), family history of breast cancer (yes or no), benign breast disease (yes or no), multivitamin use (yes or no), mammography (yes or no), and waist:hip ratio (continuous).

  • b Aspirin analyses are adjusted for NSAIDs, and NSAID analyses are adjusted for aspirin use.