Table 2

Analysis of response by cellular and molecular biomarkers at baseline

VariableCRNon-CRTotalP
Ki-67 PB LI
  mean ± SD0.57 ± 0.160.54 ± 0.230.55 ± 0.200.71a
 Median (range)0.58 (0.23, 0.77)0.50 (0.21, 0.95)0.56 (0.21, 0.95)
CP
 <4%86140.01
 ≥4%11112
p53 PB LI
 <0.289170.29
 ≥0.241115
p53 mutation
 No1016261.00
 Yes246
LOH
 No5380.12
 Yes71724
CP.p53.LOH
 0, 185130.03
 2, 341519
CP.p53
 0, 11214260.06
 2066
  • a Wilcoxon’s rank-sum test.