Table 3

Estimated RR (OR) of breast cancer and 95% CIs for quartiles of percentages of serum phospholipids fatty acida

Fatty acidsMenopausal statusOR (95% CI)
QuartileP for the overall categorical variableP for trend with the score variable
2nd3rd4th
Saturates
 14:0Preb0.48 (0.20–1.14)1.27 (0.52–3.08)2.22 (0.78–6.31)0.070.14
Post0.59 (0.24–1.44)0.72 (0.28–1.88)0.57 (0.23–1.41)0.620.37
Total0.59 (0.33–1.07)0.97 (0.52–1.81)0.91 (0.49–1.67)0.270.86
 16:0Pre1.36 (0.49–3.71)0.53 (0.19–1.43)1.20 (0.45–3.21)0.210.87
Post1.85 (0.80–4.26)2.07 (0.75–5.75)2.57 (0.99–6.61)0.260.07
Total1.57 (0.85–2.92)1.01 (0.52–1.99)1.64 (0.86–3.14)0.200.27
 18:0Pre1.01 (0.39–2.61)1.27 (0.51–3.28)2.31 (0.69–7.78)0.530.19
Post1.62 (0.64–4.11)0.88 (0.34–2.29)1.01 (0.42–2.47)0.590.65
Total1.24 (0.66–2.36)1.04 (0.55–1.97)1.18 (0.60–2.30)0.910.79
 Total SFAbPre0.62 (0.24–1.71)0.85 (0.33–2.14)1.66 (0.56–4.89)0.400.45
Post1.26 (0.49–3.21)3.91 (1.41–10.87)1.96 (0.73–5.25)0.050.09
Total0.89 (0.46–1.70)1.75 (0.92–3.34)1.46 (0.74–2.83)0.180.11
Monounsaturates
 16:1 n-7Pre1.31 (0.53–3.24)1.36 (0.55–3.37)1.07 (0.41–2.79)0.910.77
Post0.96 (0.37–2.36)1.11 (0.47–2.59)1.27 (0.54–3.09)0.920.53
Total1.09 (0.59–1.99)1.25 (0.69–2.27)1.16 (0.62–2.16)0.900.53
 18:1 n-9tPre1.40 (0.47–4.18)0.94 (0.31–2.88)1.02 (0.36 (2.88)0.850.80
Post0.67 (0.27–1.68)1.07 (0.42–2.73)0.36 (0.13–1.03)0.140.13
Total1.01 (0.52–1.98)1.08 (0.55–2.11)0.66 (0.33–1.31)0.410.25
 18:1 n-9cPre0.41 (0.16–1.06)0.52 (0.18–1.52)0.96 (0.37–2.45)0.240.91
Post1.18 (0.49–2.82)2.06 (0.84–5.05)1.84 (0.72–4.71)0.380.13
Total0.75 (0.41–1.39)1.25 (0.66–2.37)1.23 (0.65–2.32)0.410.33
 18:1 n-7cPre1.12 (0.43–2.95)0.55 (0.211.45)0.63 (0.22–1.79)0.540.31
Post0.98 (0.36–2.65)1.09 (0.45–2.62)0.72 (0.28–1.84)0.810.57
Total1.00 (0.51–1.95)0.85 (0.46–1.58)0.74 (0.38–1.46)0.810.36
 Total MUFAdPre0.44 (0.18–1.08)0.57 (0.21–1.58)1.13 (0.42–3.04)0.180.82
Post1.01 (0.42–2.44)1.55 (0.65–3.72)1.38 (0.55–3.49)0.710.37
Total0.71 (0.39–1.29)1.02 (0.54–1.94)1.15 (0.60–2.18)0.430.45
PUFA n-6Pre1.23 (0.45–3.37)1.25 (0.41–3.84)1.11 (0.42–2.94)0.970.93
 18:2 n-6Post0.91 (0.40–0.36)0.83 (0.36–1.88)1.04 (0.40–2.67)0.960.94
Total1.03 (0.55–1.92)0.99 (0.51–1.90)1.01 (0.52–1.95)0.990.98
 18:3 n-6Pre1.04 (0.46–2.33)1.07 (0.39–2.97)1.65 (0.57–4.78)0.800.39
Post1.42 (0.54–3.72)0.75 (0.29–1.92)1.46 (0.54–3.96)0.400.79
Total1.18 (0.65–2.15)0.86 (0.44–1.66)1.45 (0.73–2.89)0.450.50
 20:2n-6Pre1.71 (0.66–4.41)0.76 (0.27–2.17)0.94 (0.38–2.35)0.390.51
Post0.74 (0.28–1.98)1.15 (0.53–2.46)0.71 (0.27–1.87)0.690.83
Total1.24 (0.65–2.38)1.02 (0.56–1.84)0.82 (0.43–1.56)0.680.47
 20:3 n-6Pre2.17 (0.91–5.19)1.01 (0.41–2.49)1.90 (0.77–4.72)0.180.40
Post0.87 (0.36–2.12)1.69 (0.67–4.28)1.21 (0.48–3.03)0.450.34
Total1.25 (0.69–2.24)1.29 (0.70–2.38)1.44 (0.77–2.66)0.710.27
 20:4 n-6Pre0.69 (0.25–1.91)1.68 (0.59–4.73)0.62 (0.23–1.69)0.180.68
Post0.78 (0.34–1.80)0.61 (0.27–1.38)0.89 (0.40–1.94)0.670.64
Total0.79 (0.43–1.46)0.99 (0.55–1.81)0.81 (0.45–1.47)0.800.66
 22:4 n-6Pre1.66 (0.57–4.86)1.95 (0.65–5.85)1.86 (0.57–6.01)0.690.38
Post1.76 (0.75–4.13)1.02 (0.43–2.47)0.87 (0.35–2.17)0.460.63
Total1.53 (0.81–2.88)1.32 (0.69–2.53)1.17 (0.59–2.30)0.590.81
 22:5 n-6Pre1.17 (0.39–3.56)1.45 (0.51–4.10)1.52 (0.56–4.12)0.830.37
Post1.60 (0.72–3.59)1.76 (0.74–4.20)1.28 (0.53–3.13)0.570.49
Total1.39 (0.74–2.66)1.58 (0.83–2.99)1.43 (0.76–2.69)0.550.22
 Total n-6ePre1.31 (0.46–3.77)0.73 (0.27–1.98)0.64 (0.22–1.86)0.500.22
Post1.45 (0.65–3.25)1.09 (0.49–2.41)0.69 (0.28–1.73)0.480.49
Total1.39 (0.75–2.58)0.97 (0.53–1.78)0.70 (0.36–1.36)0.230.20
PUFA n-3Pre0.86 (0.35–2.10)1.37 (0.54–3.46)0.97 (0.41–2.26)0.760.84
 18:3 n-3Post1.46 (0.64–3.36)0.86 (0.32–2.28)0.64 (0.26–1.57)0.350.23
Total1.14 (0.63–2.06)1.14 (0.59–2.15)0.80 (0.44–1.46)0.650.48
 20:5 n-3Pre1.09 (0.48–2.46)0.56 (0.20–1.58)0.82 (0.32–2.11)0.670.46
Post0.86 (0.33–2.22)1.14 (0.43–3.01)0.91 (0.32–2.62)0.900.99
Total0.95 (0.53–1.69)0.87 (0.47–1.63)0.85 (0.44–1.65)0.960.61