Table 3

Association of SHBG with age, ethnicity, BMI, and waist circumference; regression coefficients (β)a from Generalized Estimating Equations

VariableModel 1bModel 2bModel 3b
β (nmol/liter)Pβ (nmol/liter)Pβ (nmol/liter)P
Visit age, per yr0.31030.0110.37750.00110.43640.0002
Black race−0.08640.900.87270.19−0.16550.81
Year 2 BMI, per 1 kg/m2−0.9082<0.0001−0.14520.41
Δ BMI, per 1 kg/m2−1.4084<0.0001−1.1407<0.0001
Year 2 waist circumference, per 1 cm−0.3567<0.0001
Δ Waist circumference, per 1 cm−0.10910.17
  • a Mean change in SHBG corresponding to the indicated difference in the independent variable.

  • b Each of the models also included terms for secular changes in hormone levels between the Years 2 and 7, and the Years 2 and 10 examinations.