Table 1

CMM risk associated with XRCC3 Thr241Met polymorphism

XRCC3 genotypes (Thr241Met)Cases (n = 305)Controls (n = 319)Crude OR (95% CI)Adjusted OR (95% CI)a
No.%No.%
Thr/Thr (wild type)11939.011636.41.001.00
Thr/Met (heterozygous)14848.515849.50.91 (0.65–1.28)0.94 (0.65–1.37)
Met/Met (variant)3812.54514.10.82 (0.50–1.36)0.92 (0.54–1.57)
Thr/Met + Met/Met18661.020363.60.89 (0.65–1.24)0.94 (0.66–1.34)
Met allele frequency0.3670.389
  • a OR was adjusted for age, sex, sunlight exposure, skin type, and family history of skin cancer.