Table 2

MnSOD genotype by plasma α-tocopherol availability

GenotypeAAAVVV
Plasma α:γ tocopherol ratio
 ≤6.05 mg/dl
  Cases/controls38/3779/7851/54
  ORa1.081.051.0
  95% CI0.59–2.000.63–1.76Reference
  Ptrend0.793
 >6.05
  Cases/controls34/4574/7943/45
  ORb0.760.851.0
  95% CI0.39–1.460.49–1.47Reference
  Ptrend0.407
  Pinteraction0.193
  • a The plasma α:γ ratio measures an individuals α-tocopherol availability independently of the type and amount of fat in the body and, thus, is less potentially misclassified than α-tocopherol. For both measures those with the highest value have the most available α-tocopherol.

  • b Controlling for age (continuous), sex, race (Hispanic, African American, Asian versus Caucasian), clinic and sigmoidoscopy date (±6 months).