Table 1

Demographic characteristics and polyp risk

Controls n (%)Cases with hyperplastic polyps (n = 219)Cases with adenomatous polyps (n = 437)Cases with both types of polyps (n = 138)
Cases n (%)Age- and sex-adjustedMultivariate-adjustedCases n (%)Age- and sex-adjustedMultivariate-adjustedCases n (%)Age- and sex-adjustedMultivariate-adjusted
OR95% CIORa95% CIaOR95% CIORa95% CIaOR95% CIORa95% CIa
Ageb
 <4091 (13)23 (11)1.01.023 (5)1.01.01.0
 40–49182 (26)43 (20)0.90.5–1.60.90.4–2.371 (16)1.50.9–2.62.51.0–5.915 (11)3.10.7–14.01.0
 50–59220 (31)84 (38)1.50.9–2.51.60.7–3.7134 (31)2.31.4–3.94.01.7–9.347 (34)9.32.2–39.35.31.7–16.9
 60–69170 (24)57 (26)1.30.8–2.31.40.6–3.2162 (37)3.82.3–6.36.02.6–13.755 (40)14.83.5–62.24.91.5–15.8
 70+45 (6)12 (6)1.10.5–2.31.60.5–5.047 (11)4.22.2–7.87.02.5–19.021 (15)21.54.8–96.320.05.7–70.0
P0.880.21<0.001<0.001<0.001<0.001
Sex
 Male270 (38)122 (56)1.01.0264 (60)1.01.092 (67)1.01.0
 Female438 (62)97 (44)0.50.4–0.70.60.5–0.9173 (40)0.40.3–0.50.40.3–0.646 (33)0.30.2–0.40.40.3–0.6
P<0.0010.01<0.001<0.001<0.001<0.001
Education
 ≤12 yr236 (33)76 (35)1.01.0157 (36)1.01.057 (41)1.01.0
 12+ yr472 (67)143 (65)0.90.7–1.30.70.5–1.2280 (64)1.00.7–1.20.90.6–1.381 (59)0.80.5–1.21.00.5–1.9
P0.590.230.710.540.220.99
  • a Multivariate adjustment for age, sex, BMI, HRT (yes/no), smoking (pack-years), and alcohol, where appropriate.

  • b Because of the small cell size, the <40 and 40–49 groups were collapsed for those with both kinds of polyps in the multivariate-adjusted model.