XPD codon 751 polymorphism and smoking, combined analysis
Smoking | XPD codon 751 | Whites | Blacks | Whites and blacks combined | ||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cases | Controls | ORadja | 95% CI | Test for interaction P | Cases | Controls | ORadjb | 95% CI | Test for interaction P | |||||||||
Status | ||||||||||||||||||
Never | Lys/Lys + Lys/Gln | 27 | 64 | 1.0ref | 2 | 4 | 1.0ref | |||||||||||
Never | Gln/Gln | 9 | 8 | 2.2 | 0.7–6.4 | 0 | 0 | 2.2 | 0.7–6.4 | |||||||||
Ever | Lys/Lys + Lys/Gln | 156 | 103 | 4.6 | 2.6–8.1 | 15 | 8 | 4.7 | 2.7–8.1 | |||||||||
Ever | Gln/Gln | 18 | 22 | 2.5 | 1.1–5.5 | 0.03 | 3 | 1 | 2.4 | 1.1–5.3 | 0.03 | |||||||
Years Smoked | ||||||||||||||||||
0 | Lys/Lys + Lys/Gln | 27 | 64 | 1.0ref | 2 | 4 | 1.0ref | |||||||||||
0 | Gln/Gln | 9 | 8 | 2.3 | 0.8–6.8 | 0 | 0 | 2.3 | 0.8–6.7 | |||||||||
1–34 | Lys/Lys + Lys/Gln | 69 | 69 | 3.1 | 1.7–5.7 | 9 | 6 | 3.2 | 1.8–5.8 | |||||||||
1–34 | Gln/Gln | 10 | 16 | 1.9 | 0.7–4.9 | 0.06 | 0 | 0 | 1.9 | 0.8–4.9 | 0.05 | |||||||
>35 | Lys/Lys + Lys/Glnl | 87 | 34 | 7.4 | 3.9–14 | 5 | 2 | 7.2 | 3.9–14 | |||||||||
>35 | Gln/Gln | 8 | 6 | 4.0 | 1.2–13 | 0.07 | 1 | 1 | 3.6 | 1.2–11 | 0.05 |
a Adjusted for age and sex.
b Adjusted for age, sex, and ethnicity.