Table 2

Associations between the risk of colorectal adenoma and genotypes of A171S and 169 C → T

GenotypeNo. of cases(%)No. of controls(%)Odds ratio (95% CI)a
A171S
AA343 (74.9)386 (76.6)1.00
AS100 (21.8)104 (20.6)1.12 (0.81–1.54)
SS15 (3.3)14 (2.8)1.22 (0.58–2.60)
 Total458504P = 0.41b
169 C → T
CC428 (93.4)487 (96.6)1.00
CT30 (6.6)17 (3.4)2.06 (1.10–3.83)
 Total458504
  • a Odds ratio after the matching variables (age, gender, date of sigmoidoscopy, and Kaiser Center) and ethnicity were adjusted. Additional adjustment of LDL (categorical variable by quintiles) did not change the odds ratios appreciably.

  • b Test for trend.