Table 2

Univariate relationships with survival

Status at end of follow-up
Dead n (%)Alive n (%)5-yr survival (% alive)
Age at time of diagnosis
 ≤5593 (44.7)115 (55.3)54.8
 56–64133 (39.8)201 (60.2)60.2
 65–70137 (41.6)192 (58.4)61.4
 71–79317 (51.5)298 (48.5)52.9
P a 0.05
Sex
 Male364 (47.2)407 (52.8)55.8
 Female316 (44.2)399 (55.8)57.6
P 0.48
Tumor site
 Proximal353 (48.3)378 (51.7)54.0
 Distal306 (42.9)408 (57.1)60.2
P 0.02
SEER summary stage
 Local115 (24.1)363 (75.9)79.5
 Regional309 (43.2)407 (56.8)60.5
 Distant247 (93.2)18 (6.8)7.3
P <0.01
AJCC stage
 167 (20.4)261 (79.6)83.6
 2138 (33.0)280 (67.0)71.1
 3210 (50.0)210 (50.0)53.4
 4247 (93.2)18 (6.8)7.3
P <0.01
Differentiation
 Well39 (27.3)104 (72.7)77.6
 Moderate446 (45.5)534 (54.5)56.8
 Poor146 (56.6)112 (43.4)45.7
P <0.01
Microsatellite instability status
 BAT-26 stable580 (47.9)632 (52.1)54.3
 BAT-26 unstable64 (34.8)120 (65.2)70.5
P <0.01
 TGFβRII stable593 (47.2)663 (52.8)54.7
 TGFβRII unstable54 (33.1)109 (66.9)72.4
P <0.01
  • a P is χ2 statistic for differences in 5-yr survival.