Table 1

Description of population by microsatellite instability status

BAT-26TGFβRII
BAT-26 San (%)BAT-26 Ubn (%)OR (95% CI)cTGFβRII San (%)TGFβRII Ubn (%)OR (95% CI)c
Age
 <55165 (85.0)29 (15.0)1.00175 (87.9)24 (12.1)1.00
 55–64291 (91.8)26 (8.2)0.42 (0.22–0.80)297 (92.8)23 (7.2)0.47 (0.24–0.92)
 65–70279 (89.7)32 (10.3)0.80 (0.45–1.44)285 (91.0)28 (9.0)1.01 (0.55–1.84)
 71–79477 (83.1)97 (16.9)1.24 (0.73–2.10)499 (85.0)88 (15.0)1.20 (0.69–2.10)
P<0.01<0.01
Sex
 Male651 (90.0)72 (10.0)1.00672 (91.2)65 (8.8)1.00
 Female561 (83.4)112 (16.6)1.75 (1.21–2.55)584 (85.6)98 (14.4)1.90 (1.28–2.82)
P<0.01<0.01
Tumor site
 Proximal528 (76.9)159 (23.1)1.00556 (79.8)141 (20.2)1.00
 Distal649 (96.7)22 (3.3)0.12 (0.07–0.20)664 (97.1)20 (2.9)0.14 (0.08–0.24)
P<0.01<0.01
SEER summary stage
 Local377 (84.9)67 (15.1)1.00403 (88.2)54 (11.8)1.00
 Regional573 (85.3)99 (14.7)0.76 (0.52–1.13)595 (86.1)96 (13.9)0.94 (0.62–1.43)
 Distant240 (94.5)14 (5.5)0.30 (0.13–0.67)239 (96.4)9 (3.6)0.47 (0.21–1.02)
P<0.01<0.01
AJCC stage
 1269 (85.9)44 (14.1)1.00276 (88.5)36 (11.5)1.00
 2320 (82.5)68 (17.5)1.30 (0.86–1.96)340 (84.4)63 (15.6)1.42 (0.92–2.20)
 3338 (86.5)53 (13.5)0.96 (0.62–1.48)353 (87.4)51 (12.6)1.11 (0.70–1.75)
 4240 (94.5)14 (5.5)0.36 (0.19–0.67)239 (96.4)9 (3.6)0.29 (0.14–0.61)
P<0.01<0.01
Differentiation
 Well124 (91.9)11 (8.1)1.00131 (95.6)6 (4.4)1.00
 Moderate827 (89.4)98 (10.6)1.34 (0.70–2.56)845 (90.3)91 (9.7)2.35 (1.01–5.49)
 Poor172 (72.6)65 (27.4)4.26 (2.16–8.41)188 (75.8)60 (24.2)6.97 (2.92–16.6)
P<0.01<0.01
  • a S, microsatellite stable tumor.

  • b U, microsatellite unstable tumor.

  • c OR, odds ratio and 95% CI (confidence intervals).