Association between BsmI genotype and adenomatous polyps stratified by vitamin D and calcium intakea
| Genotype | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| bb (144/134) | Bb (189/198) | BB (60/74) | |||||||||||
| OR | (95% CI) | OR | (95% CI) | OR | (95% CI) | ||||||||
| Vitamin D intake (IU) | |||||||||||||
| Highest tertile | 1.00 | (ref)b | 0.81 | (0.45–1.44) | 1.24 | (0.53–2.31) | |||||||
| Medium tertile | 1.16 | (0.62–2.17) | 0.94 | (0.42–2.13) | 0.63 | (0.22–1.80) | |||||||
| Lowest tertile | 1.40 | (0.73–2.70) | 1.26 | (0.56–2.86) | 0.24 | (0.08–0.76) | |||||||
| P for interaction | 0.094 | ||||||||||||
| Calcium intake (mg) | |||||||||||||
| Highest tertile | 1.00 | (ref) | 0.67 | (0.38–1.19) | 0.91 | (0.44–1.89) | |||||||
| Medium tertile | 0.76 | (0.40–1.46) | 1.50 | (0.66–3.40) | 1.18 | (0.41–3.40) | |||||||
| Lowest tertile | 1.22 | (0.63–2.37) | 1.48 | (0.66–3.32) | 0.34 | (0.11–1.06) | |||||||
| P for interaction | 0.255 | ||||||||||||
a Adjusted for age, gender, HRT, total caloric intake, BMI, and smoking.
b Reference category.