Table 2

Relative risks of adenomas by BsmI genotype and selected characteristics

Genotype
bb (144/134)Bb (189/198)BB (60/74)
OR(95% CI)OR(95% CI)OR(95% CI)
All subjects (age- and sex-adjusted)1.00(ref)b0.86(0.63–1.19)0.77(0.50–1.18)
All subjects (multivariate adjusted)a1.00(ref)0.86(0.62–1.20)0.71(0.46–1.11)
By gendera
 Men1.00(ref)0.92(0.58–1.45)0.70(0.38–1.29)
 Women1.00(ref)0.71(0.43–1.18)0.71(0.37–1.36)
By agea
 <60 yr1.00(ref)0.76(0.44–1.32)0.78(0.39–1.54)
 ≥60 yr1.00(ref)0.75(0.40–1.42)0.67(0.28–1.63)
By location of largest adenomaa
 Proximal1.00(ref)0.60(0.35–1.04)0.52(0.24–1.10)
 Distal1.00(ref)0.97(0.66–1.43)0.88(0.53–1.46)
 Rectum1.00(ref)0.94(0.51–1.75)0.53(0.20–1.41)
By no. of polypsa
 One1.00(ref)1.03(0.69–1.55)0.72(0.41–1.27)
 Two or more1.00(ref)0.72(0.48–1.08)0.73(0.42–1.25)
  • a Adjusted for age, gender, HRT, total caloric intake, BMI, and smoking.

  • b Reference category.