Table 2

FRR for first-degree relatives of cancer probands by site, in decreasing order of prevalence

Data from Utah [Goldgar et al.(7)] and Sweden [Dong and Hemminki (8)] are shown.
SiteUtahSweden
FRR (total)FRR (early onset)FRR (Child)FRR (sibling)
Prostate2.214.082.829.41
Breast1.833.701.862.01
Colorectal2.544.531.864.41
Lung2.552.501.683.16
Uterine1.321.75
Melanoma2.106.432.503.41
Bladder1.535.001.533.30
Non-Hodgkin’s lymphoma1.682.401.682.37
Brain/CNS1.978.951.722.37
Cervix1.731.932.39
Ovary2.042.942.52
Stomach2.081.728.82
Lip2.72
Pancreas1.25
Kidney2.461.605.26
Oral cavity1.82
Thyroid8.489.5112.42
Multiple myeloma4.294.255.62
Granulocytic leukemia2.941.693.53
Lymphocytic leukemia5.00
Hodgkin’s lymphoma1.25
Female genitalia2.222.853.97
Soft tissue sarcoma2.00
Testicular8.574.318.50
Gallbladder2.22
Larynx8.00
Total, mean2.123.782.143.37
Total, median2.154.081.863.53