Total and human DNA yields (μg/two cytobrushes or μg/one 10-ml mouthwash sample) from phase 2a of the study by method of collection
Method of collection | N | Spectrophotometry | Hybridization | ||
---|---|---|---|---|---|
Total DNA yield | A260 nm:A280 nm | Human DNA yield | |||
Median (range) | Median (range) | Median (range) | |||
Cytobrushes | 28 | 13.5b (2.0–38.2) | 1.8 (1.6–2.0) | 1.6c (0.11–7.7) | |
Mouthwash | 25 | 38.7b (11.9–124.2) | 1.8 (1.7–1.9) | 16.6c (1.55–140.3) |
a Samples were collected from women participating in the WHS and extracted by phenol-chloroform.
b P < 0.001, cytobrush versus mouthwash, Wilcoxon’s rank-sum test.
c P < 0.001, cytobrush versus mouthwash, Wilcoxon’s rank-sum test.