Table 3

WBC PAH-DNA adduct levels by ELISA in paired maternal and newborn blood samples

Ranks for mother/newborn pairsaPa
Mean ± SD/108 nucleotidesNegative ranksbPositive rankscTiesd
MaternalNewbornNo.eSumfNo.eSumfNo.e
A. WBC PAH-DNA adduct levels in all of the mother/newborn pairs (total sample)
Total cohort (n = 112)5.9 ± 8.27.9 ± 9.943155744227125P = 0.13
Nonsmoker (n = 70)5.1 ± 6.38.1 ± 9.4254982893317P = 0.05
Ex-smoker (n = 32)5.4 ± 6.78.4 ± 1.311130152216P = 0.25
Current smoker (n = 10)12.9 ± 17.54.6 ± 8.4732142P = 0.05
B. WBC PAH-DNA adduct levels in mother/newborn pairs with blood drawn concurrently (concurrent samples)
Total cohort (n = 60)5.7 ± 7.49.4 ± 11.0213822779412P = 0.04
Nonsmoker (n = 45)4.9 ± 6.89.1 ± 10.215191214759P = 0.03
Ex-smoker (n = 12)9.4 ± 9.512.7 ± 14.05246421P = 0.42
Current smoker (n = 3)3.7 ± 4.61.0 ± 0.011002P = 0.32
  • a Wilcoxon signed-ranks test.

  • b Newborn adduct level < maternal adduct levels.

  • c Newborn adduct levels > maternal adduct levels.

  • d Newborn adduct levels = maternal adduct levels.

  • e Number of mother/newborn pairs.

  • f Sum of ranks.