Table 2

WBC aromatic-DNA adduct levels by 32P-postlabeling paired maternal and newborn blood samples

Ranks for mother/newborn pairsaPa
Mean ± SD/108 nucleotidesNegative ranksbPositive rankscTiesd
MaternalNewbornNo.eSumfNo.eSumfNo.e
A. WBC aromatic-DNA adduct levels in all of the mother/newborn pairs (total sample)
Total cohort (n = 122)14.2 ± 15.416.6 ± 12.54124307948302P = 0.002
Nonsmoker (n = 79)15.0 ± 16.317.1 ± 11.3259765321041P = 0.005
Ex-smoker (n = 32)13.0 ± 15.615.7 ± 14.911185203111P = 0.22
Current smoker (n = 11)12.0 ± 4.214.7 ± 13.75306360P = 0.79
B. WBC aromatic-DNA adduct levels in mother/newborn pairs with blood drawn concurrently (concurrent samples)
Total cohort (n = 61)15.2 ± 17.817.8 ± 14.4226553912370P = 0.04
Nonsmoker (n = 46)16.6 ± 20.117.8 ± 12.418390286920P = 0.10
Ex-smoker (n = 12)10.6 ± 6.916.5 ± 20.44298490P = 0.43
Current smoker (n = 3)10.9 ± 2.223.5 ± 20.100360P = 0.11
  • a Wilcoxon signed-ranks test.

  • b Newborn adduct level < maternal adduct levels.

  • c Newborn adduct levels > maternal adduct levels.

  • d Newborn adduct levels = maternal adduct levels.

  • e Number of mother/newborn pairs.

  • f Sum of ranks.