Table 2

Case control analysis

Age (yr)Mutation statusCasesControlsOdds ratioa (95% confidence)
BRCA1+18 (25%)11 (1.6%)21.6 (9.7, 41.2)
<40BRCA2+2 (2.8%)8 (1.2%)3.3 (0.7, 15.9)
Negative51673
BRCA1+19 (9.3%)12 (1.1%)9.6 (4.6, 20.2)
40–49BRCA2+6 (2.9%)11 (0.9%)3.3 (1.2, 9.1)
Negative1791090
BRCA1+20b (3.9%)9 (0.6%)7.6 (3.4, 16.7)
≥50BRCA2+15b (3.0%)11 (0.7%)4.6 (2.1, 10.2)
Negative4731609
  • a Control group is subjects who are negative for both mutations.

  • b One patient (at Memorial Hospital) was positive for both BRCA1 and BRCA2.