Table 1

Mutation rates in cases and controls

Age (yr)InstitutionMutation positive185delAG5382insC6174delTMutation negativeTotal
Memorial Hospital (NY)8 (29%)8002028
<40Mt. Sinai (NY)2 (13%)1011315
Montreal10 (36%)5411828
Controls19 (2.7%)928673692
Memorial Hospital (NY)10 (15%)7125666
40–49Mt. Sinai (NY)6 (7%)2137682
Montreal9 (16%)6214756
Controls23 (2.1%)931110901113
Memorial Hospital (NY)10 (5%)5a15a201211a
≥50Mt. Sinai (NY)10 (6%)514161171
Montreal14 (11%)626111125
Controls20 (1.2%)361116091629
  • a One patient was positive for both 185 del AG and 6174 del T.