Table 1

Association of CYP17 genotype with the risk of ovarian cancer

GenotypeCases (n = 125)Controls (n = 144)ORa95% CIPb for trend
No.(%)No.(%)
All study subjects
A1/A145(36.0)51(35.4)1c
A1/A253(42.4)66(45.8)0.70.4–1.3
A2/A227(21.6)27(18.8)0.90.4–1.80.82
Age at menarche <13 years
A1/A121(33.9)35(44.3)1c
A1/A229(46.8)32(40.5)1.20.6–2.7
A2/A210(16.1)12(15.2)1.40.5–4.20.54
Age at menarche ≥13 years
A1/A124(35.8)16(24.6)1c
A1/A224(35.8)34(52.3)0.30.1–0.8
A2/A217(25.4)15(23.1)0.40.1–1.30.13
  • a Adjusted by multiple unconditional logistic regression for age, ethnicity, education, pregnancy history, oral contraceptive pill use, and history of total ligation.

  • b Based on the likelihood ratio test comparing models with and without a trend variable; assigned values 1, 2 and 3.

  • c Reference category.