Table 4

Comparison of molecular factors in tissue from biopsies taken from fatty and dense sites (unpaired)

	Fatty tissue at biopsy site	Dense tissue at biopsy site	P^a
Percentage of nuclear area	1.01 (0.54–2.33)^b	2.52 (1.06–5.00)	0.0004
	0.17 ^c	0.87
	n = 40	n = 51
Percentage of total collagen	11.69 (3.49–33.48)	35.54 (10.98–62.70)	0.002
	2.14	3.02
	n = 35	n = 48
Percentage of IGF-1	1.13 (0.21–2.64)	1.94 (0.75–4.06)	0.05
	−0.32	0.44
	n = 40	n = 50
Percentage of TGF-α	0.30 (0.06–0.81)	0.42 (0.11–1.32)	0.30
	−1.70	−1.21
	n = 39	n = 51
Percentage of TIMP-3	0.45 (0.05–3.63)	0.54 (0.06–5.93)	0.45
	−0.81	−0.39
	n = 40	n = 51

^a P for two sample Wilcoxon tests comparing median values.
^b Median (interquartile range) of untransformed values.
^c Mean of log-transformed data in italics to allow comparison with Tables 2<$REFLINK> and 3<$REFLINK> .