Comparison of molecular factors in tissue from biopsies taken from fatty and dense sites (unpaired)
Fatty tissue at biopsy site | Dense tissue at biopsy site | Pa | |
---|---|---|---|
Percentage of nuclear area | 1.01 (0.54–2.33)b | 2.52 (1.06–5.00) | 0.0004 |
0.17 c | 0.87 | ||
n = 40 | n = 51 | ||
Percentage of total collagen | 11.69 (3.49–33.48) | 35.54 (10.98–62.70) | 0.002 |
2.14 | 3.02 | ||
n = 35 | n = 48 | ||
Percentage of IGF-1 | 1.13 (0.21–2.64) | 1.94 (0.75–4.06) | 0.05 |
−0.32 | 0.44 | ||
n = 40 | n = 50 | ||
Percentage of TGF-α | 0.30 (0.06–0.81) | 0.42 (0.11–1.32) | 0.30 |
−1.70 | −1.21 | ||
n = 39 | n = 51 | ||
Percentage of TIMP-3 | 0.45 (0.05–3.63) | 0.54 (0.06–5.93) | 0.45 |
−0.81 | −0.39 | ||
n = 40 | n = 51 |
a P for two sample Wilcoxon tests comparing median values.
b Median (interquartile range) of untransformed values.
c Mean of log-transformed data in italics to allow comparison with Tables 2<$REFLINK> and 3<$REFLINK> .