Table 5

Estimated risk of developing breast cancer between current age and age 79, by Gail and Claus methods, for study population

Gail riska to age 79 Mean (SD)Claus risk to age 79 Mean (SD)Difference: Gail − Clausb,cPearson correlationdIntraclass correlationd
General sample (n = 317)14.2 (4.3)11.8 (5.1)2.12 (0.19)0.520.50
African-American (n = 27)6.1 (2.3)10.3 (3.4)−3.33 (0.67)0.500.24
Lesbian (n = 65)13.2 (5.0)10.9 (4.9)2.84 (0.44)0.720.66
Ashkenazi Jewish (n = 82)11.3 (3.9)9.5 (3.5)2.48 (0.39)0.510.46
All of the groups combined (n = 491)13.2 (4.7)11.2 (4.9)1.99 (0.15)0.550.50
  • a NSABP-modification of Gail model.

  • b Differences adjusted for age, age at menarche, age at first birth, number of first-degree relatives with breast cancer, number of second-degree relatives with breast cancer, and history of one or more breast biopsies.

  • c Test of difference between the Gail and Claus estimates, P < 0.001 for all of the groups.

  • d P < 0.008 among African-American group; P < 0.001 for all of the other groups.