Table 3

Association between the GSTM3 genotypea and breast cancer according to menopausal status

GSTM3 *A/*AGSTM3 *A/*BGSTM3 *B/*B
Total
 Controls (%)359 (74.8)113 (23.5)8 (1.7)
 Cases (%)361 (75.0)113 (23.5)7 (1.5)
 OR b,c (95% CI)1.01.00 (0.73–1.37)
Premenopausal
 Controls (%)160 (78.8)41 (20.2)2 (1.0)
 Cases (%)121 (73.8)42 (25.6)1 (0.6)
 OR b,c (95% CI)1.01.48 (0.89–2.47)
Postmenopausal
 Controls (%)199 (71.8)72 (26.0)6 (2.2)
 Cases (%)240 (75.7)71 (22.4)6 (1.9)
 OR b,c (95% CI)1.00.79 (0.53–1.20)
  • a Genotype data missing for two controls and two case patients.

  • b Adjusted for age, age at menarche, age at first full-term pregnancy, number of pregnancies, first-degree family history of breast cancer, and history of benign breast diseases.

  • c OR calculated for combination of *A/*B and *B/*B genotypes. Subjects with the GSTM3*A/*A genotype serve as the reference category.