Table 2

Association between the GSTM1 genotypea and breast cancer according to menopausal status

GSTM1 presentGSTM1 null
Total
 Controls (%)278 (58.2)200 (41.8)
 Cases (%)260 (54.1)221 (45.9)
 ORb,c (95% CI)1.01.23 (0.95–1.65)
Premenopausal
 Controls (%)105 (52.2)96 (47.8)
 Cases (%)89 (54.3)75 (45.7)
 OR b,c (95% CI)1.00.95 (0.61–1.46)
Postmenopausal
 Controls (%)173 (62.5)104 (37.5)
 Cases (%)171 (53.9)146 (46.1)
 OR b,c (95% CI)1.01.49 (1.03–2.15)
  • a Genotype data missing for four controls and two cases.

  • b Subjects with the GSTM1 present genotype serve as a reference category.

  • c Adjusted for age, age at menarche, age at first full-term pregnancy, number of pregnancies, first-degree family history of breast cancer, and history of benign breast diseases.