Table 2

XRCC1 codon 399 (exon 10) allele frequencies, genotype frequencies, and ORs for breast cancer

CasesControls
African Americansn = 253n = 266
 Allele
  Arg0.810.86
  Gln0.190.14
   χ2:a P = 0.02
 Genotype
  Arg/Arg164 (65%)198 (74%)
  Arg/Gln82 (32%)64 (24%)
  Gln/Gln7 (3%)4 (2%)
  Missing65
   χ2:a P = 0.05
 ORb (Arg/Gln or Gln/Gln vs. Arg/Arg) = 1.7 (1.1–2.4)
Whitesn = 386n = 381
 Allele
  Arg0.650.64
  Gln0.350.36
   χ2:a P = 0.73
 Genotype
  Arg/Arg162 (42%)164 (43%)
  Arg/Gln175 (45%)158 (41%)
  Gln/Gln49 (13%)59 (16%)
  Missing1812
   χ2:a P = 0.41
 ORb (Arg/Gln or Gln/Gln vs. Arg/Arg) = 1.0 (0.8–1.4)
  • a Comparing cases and controls.

  • b Adjusted for age.