Table 1

XRCC1 codon 194 (exon 6) allele frequencies, genotype frequencies, and ORs for breast cancer

CasesControls
African Americansn = 161n = 166
 Allele
  Arg0.950.94
  Trp0.050.06
   χ2:aP = 0.4
 Genotype
  Arg/Arg141 (91.0%)140 (87.5%)
  Arg/Trp13 (8.4%)20 (12.5%)
  Trp/Trp1 (0.6%)0 (0%)
  Missing66
   χ2:aP = 0.3
 ORb (Arg/Trp or Trp/Trp vs. Arg/Arg) = 0.7 (95% CI 0.3–1.5)
Whitesn = 251n = 234
 Allele
  Arg0.950.93
  Trp0.050.07
   χ2:a P = 0.2
 Genotype
  Arg/Arg209 (89.7%)190 (86.0%)
  Arg/Trp24 (10.3%)29 (13.1%)
  Trp/Trp0 (0%)2 (0.9%)
  Missing1813
   χ2:a P = 0.2
 ORb (Arg/Trp or Trp/Trp vs. Arg/Arg) = 0.7 (95% CI 0.4–1.3)
  • a Comparing cases and controls.

  • b Adjusted for age.