Table 1

Frequency (%) of the NQO1 gene homozygous variant among lung cancer patients and controls defined by demographic characteristics

Case (%)Control (%)
nTTaCTbCCcnTTaCTbCCc
Total8142.831.965.211233.731.065.3
Gender
 Male4452.930.167.05064.427.568.2
 Female3692.734.263.16173.233.962.9
Race
 Caucasian7802.731.565.810963.731.165.2
 Other345.941.252.9273.722.274.1
Age (yr)
 <551392.232.465.54234.028.167.9
 55–641913.134.062.82561.632.066.4
 >644842.931.066.14444.733.162.2
Smoking Status
 Never500.036.064.03964.633.661.9
 Former4323.031.066.05152.728.768.5
 Current3323.032.264.82114.731.863.5
Cigarettes/day
 1–5254.04.092.0791.325.373.4
 >5–203673.031.165.93953.532.264.3
 >20–403813.436.560.12003.028.069.0
 >401192.528.668.9474.321.374.4
Years since cessation (ex-smokers)
 1–41022.931.465.7551.832.765.5
 >4–141582.529.867.71532.024.273.8
 >14–291282.331.366.41954.130.865.1
 >29446.834.159.11121.829.568.7
Yr smoked
 ≤101612.537.550.01041.924.074.1
 >10–20422.431.066.61392.925.271.9
 >20–301151.729.668.71922.129.268.8
 >30–402281.831.666.61583.833.562.7
 >40–502043.428.468.1945.334.060.7
 >50–601263.236.560.3306.730.063.3
 >60195.342.152.640.075.025.0
Family history of cancer
 No2512.833.963.34364.430.565.1
 Yes5082.631.166.36313.531.265.3
  • a Homozygous variant.

  • b Heterozygous.

  • c Homozygous wild-type.