Table 3

Risk of ACIS by sexual history; serology for HPV-16, HPV-18, and HSV-2 antibodies; history of genital warts; and smoking status

Cases (n = 150)Controls (n = 651)ORa95% CI
n%n%
No. of partners
 12214.718228.51.0
 2–44731.318128.31.81.0 –3.1
 5+8154.027643.21.81.1 –3.1
Age at first intercourse (yrs)
 20+3221.323035.91.0
 18–193825.316726.11.50.9 –2.5
 <188053.424338.01.71.1 –2.8
Smoking history
 Never7952.733952.11.0
 Ever7147.931247.90.90.6 –1.3
 Former3724.716725.71.00.6 –1.5
 Current3422.614522.30.80.5 –1.3
History of genital warts
 Never12382.058690.01.0
 Ever2718.06510.01.50.9 –2.5
HSV-2 antibody
 Negative9570.442474.41.0
 Positive4029.614625.61.20.8 –1.9
HPV-16 antibody
 Negative9976.738870.01.0
 Positive3023.316630.00.70.5 –1.1
HPV-18 antibody
 Negative6348.841474.91.0
 Positive6651.213925.13.32.2 –4.9
  • a ORs are adjusted for age, except for those associated with a history of warts and smoking status, which are adjusted for age and number of partners.