Table 2

MVOR estimates and 95% CI for any regular NSAID use and various aspects of regular NSAID usea

CasesControlsMVORc (95% CI)
No.b(%)No.b(%)
Any regular NSAID use
 Never2306(76)2182(74)1.0
 Ever742(24)786(26)0.76 (0.66, 0.88)
ASA/non-ASA use
 Never2306(77)2182(75)1.0
 ASA390(13)418(14)0.73 (0.61, 0.87)
 Non-ASAd only316(10)330(11)0.79 (0.66, 0.96)
Duration of NSAID use (yrs)
 Never2306(80)2182(78)1.0
 ≤1153(5)173(6)0.77 (0.59, 0.98)
 2–8226(8)232(8)0.78 (0.63, 0.98)
 ≥9199(7)229(8)0.68 (0.54, 0.86)
Time since last NSAID use (yrs)
 Never2306(82)2182(78)1.0
 ≤1 (current use)387(14)469(17)0.64 (0.54, 0.77)
 2–665(2)67(2)0.76 (0.52, 1.10)
 ≥762(2)67(2)0.75 (0.51, 1.10)
Time since first NSAID use (yrs)
 Never2306(79)2182(77)1.0
 2–7195(7)208(7)0.77 (0.61, 0.98)
 8–16198(7)212(8)0.73 (0.58, 0.92)
 ≥17218(8)226(8)0.73 (0.58, 0.91)
Age at first use
 Never2306(74)2182(72)1.0
 ≤43265(8)299(10)0.69 (0.57, 0.85)
 44–49282(9)281(9)0.82 (0.66, 1.00)
 ≥50280(9)300(10)0.76 (0.61, 0.93)
  • a Defined as taken daily for at least 2 months.

  • b Numbers may not add to total because of missing values.

  • c Adjusted for age, arthritis, and benign breast cysts.

  • d Includes propionic acids, acetic acids, and oxicams.