Table 1

ORs and 95% CIs for the association of MTHFR genotype with the risk of cervical SILs

MTHFR genotypeCasesControlsORa95% CIPb for trendORc95% CIP for trend
CC 73931d1d
CT 67751.30.8–2.12.01.1–3.7
TT 10111.10.4–2.90.622.91.0–8.80.02
CT or TT77861.20.8–2.02.11.2–3.9
  • a After adjustment by unconditional multiple logistic regression for age and ethnicity.

  • b Based on the likelihood ratio test comparing models with and without a trend variable, assigned values 1, 2, and 3, representing the CC, CT, and TT categories, respectively.

  • c After adjustment by unconditional multiple logistic regression for age, ethnicity, tobacco smoking (ever versus never), alcohol drinking (ever versus never), number of sexual partners before age 20 (continuous), and HPV detection by PCR dot-blot hybridization (yes versus no).

  • d Reference category.