Table 6

OR of lung cancer related to GSTT1 genotype and POR of GSTT1 genotype and asbestos exposure

StudyOR − main effectaPORb
OR95% CIOR95% CIc
(France 1)0.70.4–1.21.60.7–3.7
(France 2)1.30.7–2.31.10.5–2.7
(Finland)1.00.4–2.3
Pooled AnalysisNA1.10.6–2.0
Test for heterogeneity (P)0.72
  • a OR of lung cancer related to GSTT1-null genotype, based on case control studies, adjusted for gender, age, and pack-years of tobacco smoking.

  • b POR of GSTT1-null genotype for asbestos exposure, adjusted for gender, age, and pack-years of tobacco smoking (and study in the pooled analysis).

  • c 95% CI.