Table 4

Geographic distribution of four metabolic gene alleles in Caucasian populations

CountryCYP1A1*2ANAT2*5GSTM1*0GSTT1*0
Canada0.0602 (299)aNAb0.513 (304)0.172 (274)
DenmarkNA0.466 (426)0.536 (537)0.129 (358)c
Finland0.0621 (145)0.465 (414)0.469 (482)0.130 (385)c
France0.0527 (171)0.393 (244)0.534 (1184)0.168 (512)
Germany0.0442 (882)c0.461 (701)0.516 (734)0.195 (487)
Italy0.0891 (303)0.457 (550)0.494 (810)0.163 (553)
Netherlands0.0335 (419)cNA0.504 (419)0.229 (419)
Norway0.0795 (107)0.487 (371)0.506 (423)NA
PortugalNA0.457 (257)0.583 (501)NA
Saudi ArabiaNANA0.563 (895)NA
SlovakiaNANA0.512 (332)0.180 (322)
Slovenia0.0654 (107)NA0.520 (102)0.255 (102)
SpainNANA0.497 (312)0.205 (312)
Sweden0.0743 (512)0.496 (420)0.559 (544)0.130 (423)c
UK0.0694 (310)NA0.578 (1122)c0.205 (922)
US0.0662 (649)0.432 (385)0.543 (1751)0.276 (286)
  • a Numbers in parentheses denote the number of subjects tested.

  • b NA, not available; US, United States; UK, United Kingdom.

  • c Statistically significant difference (P < 0.05, by χ2 test) compared with the rest of the population combined.