Table 1

Odds ratios of colorectal cancer for quintiles of serum IGF-I, and of three different measures of IGFBP-3a

QuintilesP for trend
12345
IGF-I1.001.49 (0.63–3.52)1.30 (0.56–3.02)1.52 (0.67–3.47)1.88 (0.72–4.91)0.25
IGFBP-3
 IRMA-Immunotech1.001.70 (0.78–3.70)1.15 (0.50–2.66)0.92 (0.40–2.12)2.46 (1.09–5.57)0.19
 ELISA-DSL1.000.89 (0.41–1.94)0.69 (0.30–1.57)1.23 (0.55–2.76)1.24 (0.54–2.86)0.49
IGF-I adjusted for IGFBP-3; IGFBP-3 measured by
 IRMA-Immunotech1.001.59 (0.73–3.47)0.56 (0.23–1.39)1.43 (0.61–3.36)1.23 (0.47–3.22)0.70
 ELISA-DSL1.001.48 (0.65–3.35)1.07 (0.47–2.43)1.23 (0.52–2.95)1.03 (0.39–2.69)0.93
  • a Study based on 102 cases of colorectal cancer and 200 matched controls; see Kaaks et al., (3) for details.