Table 6

Interactive effects of dietary nitrite and vitamin C on risk of esophageal and gastric cancer, from United States multicenter, population-based study

Results are ORs and 95% CIs.
Esophageal adenocarcinoma vs. controlGastric cardia adenocarcinoma vs. controlEsophageal squamous cell carcinoma vs. controlNoncardia gastric cancer vs. control
High C, low nitritea1.0 (referent)1.0 (referent)1.0 (referent)1.0 (referent)
High C, high nitrite1.65 (1.05–2.61)1.40 (0.88–2.22)1.50 (0.84–2.67)2.10 (1.36–3.25)
Low C, low nitrite1.76 (1.12–2.78)1.52 (0.97–2.39)2.51 (1.46–4.32)2.25 (1.46–3.47)
Low C, high nitrite2.72 (1.73–4.27)2.18 (1.38–3.43)3.92 (2.28–6.74)2.95 (1.90–4.59)
  • a High, above the median intake level in the control population; low, below the median intake level in the control population.