Appendix 1.

Appendix HLA class II allele and haplotype distribution among Senegalese study population controls in comparison with other HLA-typed West African populations

DRB1 allelen%Senegal [43]aDRB1-DQB1 haplotypen%Gambia [44]bMalawi [44]b
010120.5%0.6%0101-050120.5%DR1-DQ5: 4.1%4.6%
010292.4%0.6%0102-050192.4%
0301174.5%9.0%0301-0201/2164.3%DR0301-DQw2: 2.7%7.3%
0302297.7%2.8%0301-020310.3%
040120.5%0301-050110.3%
040330.8%0.4%0302-0402287.4%DR0302-DQw4: 3.4%6.4%
0405143.7%0.6%0302-050110.3%
0701133.5%7.5%0401-030110.3%DR4-DQB*0301: 0.1%0.0%
08012.8%0401-030210.3%DR4-DQB1*0302: 4.5%2.7%
08027.2%0403-030230.8%
08031.3%0405-0201/230.8%DR4-DQw2: 0.9%0.3%
0804154.0%0405-0302112.9%
080641.1%0701-0201/2123.2%DR7-DQw2: 4.3%4.3%
0901143.7%1.4%0701-020310.3%
10014512.0%4.3%0804-0301143.7%DR8-DQw7: 3.0%4.3%
1101359.3%9.7%0804-060410.3%DR3-DQw6: 0.3%0.0%
1102308.0%6.0%0806-060241.1%
11030.2%0901-0201/2133.5%DR9-DQw2: 7.1%10.4%
110410.3%0.7%0901-020310.3%
120130.8%0.4%1001-05014512.0%DR10-DQw5: 8.9%0.9%
120210.3%1101-020310.3%DR1101-DQw2: 0.2%0.0%
1301236.1%4.3%1101-0301184.8%DR1101-DQ0301: 4.2%6.4%
1302349.0%4.5%1101-050151.3%DR1101-DQw5: 0.1%0.0%
1303112.9%1.5%1101-050210.3%
13045614.9%27.1%1101-060292.4%DR1101-DQw6: 2.0%8.5%
13050.5%1101-060420.5%
132261.6%1102-0301287.4%
140110.3%0.8%1102-030210.3%
150310.3%1104-030110.3%
16011.6%1201-030130.8%DR12-DQ0301: 0.4%0.0%
160271.9%1202-060210.3%
 Missing21301-0201/220.5%
 Total (missing)3761301-030220.5%
DQB1 allele n %1301-060210.3%DR13-DQw6: 3.6%4.2%
0201/24913.0%1301-0603174.5%
020341.1%1302-0201/210.3%DR13-DQw2: 0.6%0.0%
030112833.9%1302-0501225.9%DR13-DQw5: 0.3%0.3%
0302195.0%1302-050210.3%DR1302-DQw1: 16.4%7.6%
0402287.4%1302-060461.6%
05018622.8%1302-060510.3%
050292.4%1302-060930.8%
050310.3%1303-0201/220.5%1303-0301: 2.2%0.9%
0602164.2%1303-030192.4%1304-0301: 27.3%3.0%
0603236.1%1304-03015414.4%
0604112.9%1304-030210.3%
060510.3%1304-060410.3%
060930.8%1322-060351.3%
Missing01322-060410.3%
 Total (missing)3781401-050310.3%DR14-DQw1: 0.5%0.9%
1503-030100.0%
1503-060210.3%DR15-DQw6: 0.8%13.4%
1602-050271.9%DR16-DQw5: 1.5%0.3%
Missing2
Total (missing)376
  • a Tiercy et al.: Mandenka (Mandenkalu) of Senegal.

  • b Hill et al: The Gambia (West Africa) and Malawi (South-Central Africa).