Table 3

Crude and adjusted ORs for the association between cervical carcinoma and a priori hypothesized class II HLA alleles and haplotypes

DQB1 and DRB1 allelesCases vs. HPV + controls Crude OR (95% CI)Cases vs. HPV − controls Crude OR (95% CI)Cases vs. HPV-controlsAdjusted ORa (95% CI)Cases vs. combined controls Crude OR (95% CI)Cases vs. combined controls Adjusted ORa (95% CI)
DQB1*0201/21.4 (0.7–2.8)2.9 (1.3–6.3)1.1 (0.4–3.1)2.1 (1.1–3.9)1.2 (0.5–2.8)
DQB1*030.6 (0.3–1.2)0.8 (0.4–1.6)0.8 (0.4–1.4)0.8 (0.4–1.9)
DQB1*06020.5 (0.1–2.2)0.9 (0.2–3.3)0.7 (0.2–2.4)0.6 (0.1–2.7)
DRB1*130.5 (0.6–1.1)0.5 (0.3–1.0)0.5 (0.2–1.4)0.5 (0.3–1.0)0.5 (0.2–1.1)
DRB1*110.8 (0.3–1.7)0.9 (0.4–1.8)0.8 (0.4–1.6)1.0 (0.4–2.2)
DRB1*1101-DQB1*03011.4 (0.5–3.5)3.6 (1.2–10.6)7.4 (1.5–36.5)2.1 (0.9–4.9)2.6 (1.0–7.1)
  • a Adjusted for birthplace, no. of live-born infants, age, and other alleles in Table.