Table 3.

Comparisons of non-Hispanic white versus non-Hispanic black model–predicted serum cotinine levels, by sex, FTC nicotine, cigarette menthol, body weight, and cigarettes smoked per day: NHANES 2001–2006

ModelaSexbFTC nicotine, mgcMentholbBody weight, lbsb, dCigarettes per dayNon-Hispanic white–predicted cotinine (N = 1,145)Non-Hispanic black–predicted cotinine (N = 486)Difference (non-Hispanic white–black)Significancee
1F0.8x1505105.4202.1–96.7*
x15010178.1275.7–97.7*
x15015203.9288.8–85.0*
x15020211.1290.9–79.7*
x15025213.0291.2–78.1*
x200594.7197.8–103.2*
x20010148.0266.7–118.7*
x20015175.0276.0–100.9*
x20020186.5277.0–90.6*
x20025191.0277.2–86.2*
1.1x1505114.5189.8–75.3*
x15010186.3279.5–93.2*
x15015210.6311.3–100.7*
x15020217.3320.8–103.6*
x15025219.0323.5–104.5*
x2005104.7184.0–79.2*
x20010157.2276.6–119.4*
x20015182.5301.7–119.3*
x20020192.8307.4–114.6*
x20025196.7308.6–111.9*
M0.8x1505162.3198.0–35.8
x15010239.4261.5–22.1
x15015246.9275.4–28.5
x15020247.5278.0–30.5
x15025247.6278.5–31.0
x2005133.5190.1–56.6*
x20010211.4253.0–41.6*
x20015222.9263.4–40.5*
x20020224.3265.0–40.7*
x20025224.5265.2–40.7*
1.1x1505170.4196.5–26.1
x15010246.5265.1–18.5
x15015253.7294.0–40.3*
x15020254.3304.7–50.5*
x15025254.3308.5–54.2*
x2005141.3182.2–40.9*
x20010218.2260.1–41.9*
x20015229.2285.7–56.6*
x20020230.4293.0–62.5*
x20025230.6294.9–64.3*
2F0.8N1505109.3201.8–92.6*
N15010180.9304.0–123.1*
N15015204.1322.4–118.2*
N15020210.1325.1–115.0*
N15025211.5325.5–113.9*
N200597.4211.8–114.4*
N20010151.5297.5–146.0*
N20015177.1306.7–129.5*
N20020187.2307.5–120.3*
N20025190.9307.6–116.7*
Y150593.5196.9–103.4*
Y15010170.3252.5–82.2*
Y15015203.4276.7–73.3*
Y15020214.4286.2–71.8*
Y15025217.8289.8–72.0*
Y200581.9177.4–95.6*
Y20010134.9249.3–114.5*
Y20015168.0269.5–101.6*
Y20020185.0274.4–89.4*
Y20025193.0275.5–82.5*
1.1N1505117.9162.1–44.3
N15010188.2280.6–92.4*
N15015209.5326.2–116.7*
N15020214.7340.0–125.3*
N15025215.9343.9–128.0*
N2005106.6176.2–69.6*
N20010159.9293.8–133.9*
N20015183.4320.5–137.1*
N20020192.2325.3–133.2*
N20025195.3326.2–130.9*
Y1505107.1185.8–78.8*
Y15010182.7254.3–71.6*
Y15015214.3285.1–70.7*
Y15020224.8297.1–72.3*
Y15025228.1301.7–73.6*
Y200598.1174.3–76.2*
Y20010149.5256.8–107.3*
Y20015180.1280.3–100.2*
Y20020195.6285.8–90.3*
Y20025202.9287.1–84.3*
M0.8N1505163.9182.1–18.2
N15010238.5274.7–36.2
N15015245.4303.2–57.8
N15020245.9310.5–64.5
N15025246.0312.2–66.2
N2005134.9185.9–51.0
N20010211.5275.8–64.3*
N20015222.5292.5–70.0*
N20020223.8295.1–71.3*
N20025223.9295.5–71.6*
Y1505152.2283.3–131.1*
Y15010242.4282.3–39.9
Y15015253.3281.6–28.3
Y15020254.3281.2–26.9
Y15025254.4280.9–26.5
Y2005121.7191.9–70.1*
Y20010211.7234.1–22.5
Y20015228.7252.7–24.0
Y20020231.2260.2–29.1
Y20025231.5263.2–31.7
1.1N1505171.6154.017.6
N15010244.1233.111.0
N15015250.4282.0–31.6
N15020250.9307.9–57.0
N15025250.9320.6–69.7*
N2005142.4152.3–9.9
N20010217.1255.1–38.0
N20015227.2295.6–68.4*
N20020228.3308.3–80.0*
N20025228.4312.1–83.6*
Y1505163.6248.0–84.3*
Y15010254.2264.4–10.2
Y15015265.1275.0–9.9
Y15020266.1281.6–15.5
Y15025266.2285.8–19.6
Y2005132.6180.2–47.5*
Y20010222.6235.0–12.3
Y20015239.5259.8–20.3
Y20020242.0269.9–28.0
Y20025242.3273.8–31.5
  • aModel 1: cpd + continuous nicotine + sex + continuous weight. Model 2: Model 1 terms + menthol + (nicotine × menthol) potential effect modification terms. (Both models were stratified by race/ethnicity.)

  • b“x” means the factor was not considered in the model.

  • cNicotine comparisons at 0.8 and 1.1 were chosen according to common-overlap considerations (Fig. 1).

  • dWeight comparisons at 150 and 200 were chosen to roughly cover the middle half of all race × sex distributions (data not shown).

  • eAsterisks (*) indicate P < 0.05 for H0: non-Hispanic white = non-Hispanic black–predicted cotinine geometric means; the standard errors of prediction were manually combined to create a comparison standard error (not adjusted for design effects and treated as if independent across race/ethnicity, which may err on the side of too many falsely significant results for each test run at the 5% level of significance).