PT  - JOURNAL ARTICLE
AU  - Cuthbertson, Carmen C.
AU  - Nichols, Hazel B.
AU  - Tan, Xianming
AU  - Kucharska-Newton, Anna
AU  - Heiss, Gerardo
AU  - Joshu, Corinne E.
AU  - Platz, Elizabeth A.
AU  - Evenson, Kelly R.
TI  - Associations of Leisure-Time Physical Activity and Television Viewing with Life Expectancy Cancer-Free at Age 50: The ARIC Study
AID  - 10.1158/1055-9965.EPI-20-0870
DP  - 2020 Sep 25
TA  - Cancer Epidemiology Biomarkers & Prevention
4099  - http://cebp.aacrjournals.org/content/early/2020/10/23/1055-9965.EPI-20-0870.short
4100  - http://cebp.aacrjournals.org/content/early/2020/10/23/1055-9965.EPI-20-0870.full
AB  - Background: Physical activity has been associated with longer chronic disease–free life expectancy, but specific cancer types have not been investigated. We examined whether leisure-time moderate-to-vigorous physical activity (LTPA) and television (TV) viewing were associated with life expectancy cancer-free.Methods: We included 14,508 participants without a cancer history from the Atherosclerosis Risk in Communities (ARIC) study. We used multistate survival models to separately examine associations of LTPA (no LTPA, <median, ≥median) and TV viewing (seldom/never, sometimes, often/very often) with life expectancy cancer-free at age 50 from invasive colorectal, lung, prostate, and postmenopausal breast cancer. Models were adjusted for age, gender, race, ARIC center, education, smoking, and alcohol intake.Results: Compared with no LTPA, participants who engaged in LTPA ≥median had a greater life expectancy cancer-free from colorectal [men-2.2 years (95% confidence interval (CI), 1.7–2.7), women-2.3 years (95% CI, 1.7–2.8)], lung [men-2.1 years (95% CI, 1.5–2.6), women-2.1 years (95% CI, 1.6–2.7)], prostate [1.5 years (95% CI, 0.8–2.2)], and postmenopausal breast cancer [2.4 years (95% CI, 1.4–3.3)]. Compared with watching TV often/very often, participants who seldom/never watched TV had a greater colorectal, lung, and postmenopausal breast cancer-free life expectancy of ∼1 year.Conclusions: Participating in LTPA was associated with longer life expectancy cancer-free from colorectal, lung, prostate, and postmenopausal breast cancer. Viewing less TV was associated with more years lived cancer-free from colorectal, lung, and postmenopausal breast cancer.Impact: Increasing physical activity and reducing TV viewing may extend the number of years lived cancer-free.