Automated Quantitative Measures of Terminal Duct Lobular Unit Involution and Breast Cancer Risk

Kevin H. Kensler; Emily Z.F. Liu; Suzanne C. Wetstein; Allison M. Onken; Christina I. Luffman; Gabrielle M. Baker; Laura C. Collins; Stuart J. Schnitt; Vanessa C. Bret-Mounet; Mitko Veta; Josien P.W. Pluim; Ying Liu; Graham A. Colditz; A. Heather Eliassen; Susan E. Hankinson; Rulla M. Tamimi; Yujing J. Heng

doi:10.1158/1055-9965.EPI-20-0723

Research Articles

Automated Quantitative Measures of Terminal Duct Lobular Unit Involution and Breast Cancer Risk

Kevin H. Kensler, Emily Z.F. Liu, Suzanne C. Wetstein, Allison M. Onken, Christina I. Luffman, Gabrielle M. Baker, Laura C. Collins, Stuart J. Schnitt, Vanessa C. Bret-Mounet, Mitko Veta, Josien P.W. Pluim, Ying Liu, Graham A. Colditz, A. Heather Eliassen, Susan E. Hankinson, Rulla M. Tamimi and Yujing J. Heng

Kevin H. Kensler

1Division of Population Sciences, Dana-Farber Cancer Institute, Boston, Massachusetts.

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Emily Z.F. Liu

2Department of Pathology, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, Massachusetts.

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Suzanne C. Wetstein

3Medical Image Analysis Group, Eindhoven University of Technology, Eindhoven, the Netherlands.

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Allison M. Onken

2Department of Pathology, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, Massachusetts.

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Christina I. Luffman

2Department of Pathology, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, Massachusetts.

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Gabrielle M. Baker

2Department of Pathology, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, Massachusetts.

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Laura C. Collins

2Department of Pathology, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, Massachusetts.

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Stuart J. Schnitt

4Department of Pathology, Harvard Medical School and Brigham and Women's Hospital; Dana-Farber Cancer Institute, Boston, Massachusetts.

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Vanessa C. Bret-Mounet

2Department of Pathology, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, Massachusetts.

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Mitko Veta

3Medical Image Analysis Group, Eindhoven University of Technology, Eindhoven, the Netherlands.

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Josien P.W. Pluim

3Medical Image Analysis Group, Eindhoven University of Technology, Eindhoven, the Netherlands.

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Ying Liu

5Division of Public Health Sciences, Department of Surgery, Washington University School of Medicine and Alvin J. Siteman Cancer Center, St Louis, Missouri.

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Graham A. Colditz

5Division of Public Health Sciences, Department of Surgery, Washington University School of Medicine and Alvin J. Siteman Cancer Center, St Louis, Missouri.

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A. Heather Eliassen

6Channing Division of Network Medicine, Department of Medicine, Harvard Medical School, Brigham and Women's Hospital, Boston, Massachusetts.

7Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts.

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Susan E. Hankinson

6Channing Division of Network Medicine, Department of Medicine, Harvard Medical School, Brigham and Women's Hospital, Boston, Massachusetts.

8Department of Biostatistics and Epidemiology, School of Public Health and Health Sciences, University of Massachusetts Amherst, Amherst, Massachusetts.

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Rulla M. Tamimi

6Channing Division of Network Medicine, Department of Medicine, Harvard Medical School, Brigham and Women's Hospital, Boston, Massachusetts.

7Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts.

9Department of Population Health Sciences, Weill Cornell Medicine, New York, New York.

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Yujing J. Heng

2Department of Pathology, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, Massachusetts.

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For correspondence: yheng@bidmc.harvard.edu

DOI: 10.1158/1055-9965.EPI-20-0723 Published November 2020

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Cancer Epidemiology Biomarkers & Prevention: 29 (11)

November 2020
Volume 29, Issue 11

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Automated Quantitative Measures of Terminal Duct Lobular Unit Involution and Breast Cancer Risk

Cancer Epidemiol Biomarkers Prev November 1 2020 (29) (11) 2358-2368; DOI: 10.1158/1055-9965.EPI-20-0723

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Automated Quantitative Measures of Terminal Duct Lobular Unit Involution and Breast Cancer Risk

Cancer Epidemiol Biomarkers Prev November 1 2020 (29) (11) 2358-2368; DOI: 10.1158/1055-9965.EPI-20-0723

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