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Cancer Epidemiology, Biomarkers & Prevention
Cancer Epidemiology, Biomarkers & Prevention
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Genetic Variants in Epigenetic Pathways and Risks of Multiple Cancers in the GAME-ON Consortium

Reka Toth, Dominique Scherer, Linda E. Kelemen, Angela Risch, Aditi Hazra, Yesilda Balavarca, Jean-Pierre J. Issa, Victor Moreno, Rosalind A. Eeles, Shuji Ogino, Xifeng Wu, Yuanqing Ye, Rayjean J. Hung, Ellen L. Goode and Cornelia M. Ulrich
Reka Toth
1National Center for Tumor Diseases and German Cancer Research Center (DKFZ), Heidelberg, Germany.
2Division of Epigenomics and Cancer Risk Factors, German Cancer Research Center (DKFZ), Heidelberg, Germany.
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Dominique Scherer
1National Center for Tumor Diseases and German Cancer Research Center (DKFZ), Heidelberg, Germany.
3Institute of Medical Biometry and Informatics, University of Heidelberg, Heidelberg, Germany.
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Linda E. Kelemen
4Medical University of South Carolina and Hollings Cancer Center, Charleston, South Carolina.
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Angela Risch
2Division of Epigenomics and Cancer Risk Factors, German Cancer Research Center (DKFZ), Heidelberg, Germany.
5Division of Cancer Research and Epigenetics, Department of Molecular Biology, University of Salzburg, Salzburg, Austria.
6Cancer Cluster Salzburg, Salzburg, Austria.
7Translational Lung Research Center Heidelberg (TLRC-H), Member of the German Center for Lung Research (DZL), Heidelberg, Germany.
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Aditi Hazra
8Brigham and Women's Hospital, Harvard Medical School, Harvard T.H. Chan School of Public Health, Boston, Massachusetts.
9Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.
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Yesilda Balavarca
1National Center for Tumor Diseases and German Cancer Research Center (DKFZ), Heidelberg, Germany.
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Jean-Pierre J. Issa
10School of Medicine, Temple University, Philadelphia, Pennsylvania.
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Victor Moreno
11Catalan Institute of Oncology, IDIBELL, L'Hospitalet de Llobregat, Barcelona, Catalonia, Spain.
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Rosalind A. Eeles
12The Institute of Cancer Research, London, United Kingdom.
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Shuji Ogino
13Department of Pathology, Brigham and Women's Hospital, and Harvard Medical School, Boston, Massachusetts.
14Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.
15Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts.
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Xifeng Wu
16Department of Epidemiology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
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Yuanqing Ye
16Department of Epidemiology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
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Rayjean J. Hung
17Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, Ontario, Canada.
18University of Toronto, Toronto, Canada.
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Ellen L. Goode
19Mayo Clinic College of Medicine, Rochester, Minnesota.
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Cornelia M. Ulrich
1National Center for Tumor Diseases and German Cancer Research Center (DKFZ), Heidelberg, Germany.
20Fred Hutchinson Cancer Research Center, Seattle, Washington.
21Huntsman Cancer Institute, Salt Lake City, Utah.
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  • For correspondence: Neli.ulrich@hci.utah.edu
DOI: 10.1158/1055-9965.EPI-16-0728 Published June 2017
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Article Information

Volume 26, Issue 6, pp. 816-825

DOI 
https://doi.org/10.1158/1055-9965.EPI-16-0728
PubMed 
28115406

Published By 
American Association for Cancer Research
Print ISSN 
1055-9965
Online ISSN 
1538-7755
History 
  • Received September 9, 2016
  • Revision received December 16, 2016
  • Accepted December 19, 2016
  • Published first January 23, 2017.

Article Versions

  • Previous version (January 23, 2017 - 07:25).
  • Previous version (May 18, 2017 - 00:07).
  • You are viewing the most recent version of this article.
Copyright & Usage 
©2017 American Association for Cancer Research.

Author Information

  1. Reka Toth1,2,
  2. Dominique Scherer1,3,
  3. Linda E. Kelemen4,
  4. Angela Risch2,5,6,7,
  5. Aditi Hazra8,9,
  6. Yesilda Balavarca1,
  7. Jean-Pierre J. Issa10,
  8. Victor Moreno11,
  9. Rosalind A. Eeles12,
  10. Shuji Ogino13,14,15,
  11. Xifeng Wu16,
  12. Yuanqing Ye16,
  13. Rayjean J. Hung17,18,
  14. Ellen L. Goode19, and
  15. Cornelia M. Ulrich1,20,21,*;
  16. on behalf of the OCAC, CORECT*, TRICL, ELLIPSE**, DRIVE, and GAME-ON consortiaa
  1. 1National Center for Tumor Diseases and German Cancer Research Center (DKFZ), Heidelberg, Germany.
  2. 2Division of Epigenomics and Cancer Risk Factors, German Cancer Research Center (DKFZ), Heidelberg, Germany.
  3. 3Institute of Medical Biometry and Informatics, University of Heidelberg, Heidelberg, Germany.
  4. 4Medical University of South Carolina and Hollings Cancer Center, Charleston, South Carolina.
  5. 5Division of Cancer Research and Epigenetics, Department of Molecular Biology, University of Salzburg, Salzburg, Austria.
  6. 6Cancer Cluster Salzburg, Salzburg, Austria.
  7. 7Translational Lung Research Center Heidelberg (TLRC-H), Member of the German Center for Lung Research (DZL), Heidelberg, Germany.
  8. 8Brigham and Women's Hospital, Harvard Medical School, Harvard T.H. Chan School of Public Health, Boston, Massachusetts.
  9. 9Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.
  10. 10School of Medicine, Temple University, Philadelphia, Pennsylvania.
  11. 11Catalan Institute of Oncology, IDIBELL, L'Hospitalet de Llobregat, Barcelona, Catalonia, Spain.
  12. 12The Institute of Cancer Research, London, United Kingdom.
  13. 13Department of Pathology, Brigham and Women's Hospital, and Harvard Medical School, Boston, Massachusetts.
  14. 14Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.
  15. 15Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts.
  16. 16Department of Epidemiology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  17. 17Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, Ontario, Canada.
  18. 18University of Toronto, Toronto, Canada.
  19. 19Mayo Clinic College of Medicine, Rochester, Minnesota.
  20. 20Fred Hutchinson Cancer Research Center, Seattle, Washington.
  21. 21Huntsman Cancer Institute, Salt Lake City, Utah.
  22. aMembers of GAME-ON ELLIPSE.
  1. ↵*Corresponding Author:
    Cornelia M. Ulrich, Huntsman Cancer Institute, 2000 Circle of Hope Drive Room 4165, Salt Lake City, UT 84112. Phone: 801-213-5716; Fax: 801-585-0900; E-mail: Neli.ulrich{at}hci.utah.edu
  1. R. Toth, D. Scherer, R.J. Hung, E.L. Goode, and C.M. Ulrich contributed equally to this article.

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Cancer Epidemiology Biomarkers & Prevention: 26 (6)
June 2017
Volume 26, Issue 6
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Genetic Variants in Epigenetic Pathways and Risks of Multiple Cancers in the GAME-ON Consortium
Reka Toth, Dominique Scherer, Linda E. Kelemen, Angela Risch, Aditi Hazra, Yesilda Balavarca, Jean-Pierre J. Issa, Victor Moreno, Rosalind A. Eeles, Shuji Ogino, Xifeng Wu, Yuanqing Ye, Rayjean J. Hung, Ellen L. Goode and Cornelia M. Ulrich on behalf of the OCAC, CORECT*, TRICL, ELLIPSE**, DRIVE, and GAME-ON consortiaa
Cancer Epidemiol Biomarkers Prev June 1 2017 (26) (6) 816-825; DOI: 10.1158/1055-9965.EPI-16-0728

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Genetic Variants in Epigenetic Pathways and Risks of Multiple Cancers in the GAME-ON Consortium
Reka Toth, Dominique Scherer, Linda E. Kelemen, Angela Risch, Aditi Hazra, Yesilda Balavarca, Jean-Pierre J. Issa, Victor Moreno, Rosalind A. Eeles, Shuji Ogino, Xifeng Wu, Yuanqing Ye, Rayjean J. Hung, Ellen L. Goode and Cornelia M. Ulrich on behalf of the OCAC, CORECT*, TRICL, ELLIPSE**, DRIVE, and GAME-ON consortiaa
Cancer Epidemiol Biomarkers Prev June 1 2017 (26) (6) 816-825; DOI: 10.1158/1055-9965.EPI-16-0728
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